Immuno-gG ® SBI


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Immuno-gG ® SBI is a dairy-free immunoglobulin concentrate formula that supports healthy digestion and immune function. This purified source of immunoglobulin G (IgG) is derived from bovine serum making it free of lactose, casein and β-lactoglobulins.

Life Begins in the Gut
The digestive system is the foundation of getting and staying healthy. Although there are many benefits to a digestive system running optimally, some key advantages include a healthy immune system and the protection against harmful bacteria, viruses, yeast and fungus. Immunoglobulins play an important role in both the support of healthy digestion and immune function. They are proteins that function as antibodies to neutralize and eliminate unwanted toxins like lipopolysaccharide (LPS) before they have a chance to activate the immune system or induce inflammation.

Mechanism of Action
The method by which immunoglobulins and other bioactive peptides found in SBI help to maintain gut barrier function is believed to involve the direct binding of microbial components found naturally in the digestive tract. In vitro studies have demonstrated that SBI binds to many potentially toxic microbial antigens that appear normally in the intestinal tract. Immunoglobulins bind microbes and toxins in the GI tract and eliminate them prior to immune system activation. These microbial antigens (e.g. bacterial endotoxin) that are present in the intestinal tract due to the normal breakdown and turnover of resident bacteria and/or result from the consumption of contaminated food or water have the potential to activate the intestinal immune system. By binding to these microbial antigens, SBI helps to create a complex so large that it has difficulty penetrating the intestinal epithelium, allowing instead for the antigenic complex to remain in the intestinal lumen and exit the intestinal tract following normal peristalsis. To demonstrate this action, Detzel, et al.1 conducted a study using an in vitro cell culture model to show that binding of antigens by the immunoglobulins in SBI prevented translocation of the antigens across epithelial cells, which in turn avoided the production of inflammatory cytokines by adjacent immune cells. These results suggest that the binding action of immunoglobulins in SBI helps keep toxic antigens within the lumen of the intestinal tract and avoid their absorption into the blood stream, which may help manage gut permeability and immune activation that occur with exposure to such antigens. By binding to microbes and toxins, Immuno-gG ® SBI enhances microbiome balance and facilitates gut barrier strength, resetting immune tolerance.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.