Chronic joint pain, tendon and ligament injuries, and degenerative conditions can be complex. Regenerative injection therapies are procedural options that may be considered after an individualized clinical assessment. Services offered may include platelet-rich plasma (PRP), prolotherapy, Prolozone, ozone injections, and perineural injection therapy.
Dr. Kendall Perrine, ND will review your health history, goals, and the potential benefits, limitations, risks, and alternatives to help determine whether an approach may be appropriate for you.
Platelet-Rich Plasma (PRP) Injections
PRP therapy uses a concentrated sample of a patient’s own blood platelets. During the procedure, a small blood sample is collected and processed, then the platelet-rich plasma is injected into the treatment area. Platelets contain growth factors involved in normal tissue-repair processes.
Whether PRP is appropriate depends on a clinical evaluation, the treatment area, and your individual circumstances.
Prolotherapy
Prolotherapy is an injection technique that may use a dextrose-based solution, sometimes with lidocaine, in selected ligaments, tendons, or joints. The procedure is intended to create a localized response at the treatment site. Treatment decisions are individualized and depend on a clinical assessment.
Your consultation will cover potential benefits, limitations, risks, alternatives, and what to expect before and after treatment.
Ozone Injections & Prolozone
Ozone injection therapy uses a gas generated from oxygen and may be administered into a muscle or joint as part of an individualized care plan. Prolozone is a term sometimes used when prolotherapy and ozone injection techniques are combined within an individualized treatment plan. These services are considered only after a consultation and discussion of your history, goals, risks, alternatives, and expected course of care.
Ozone therapy is not evaluated or approved by the FDA for the treatment of any medical condition. Individual experiences and outcomes vary.
Further reading: Systematic review and meta-analysis of intra-articular ozone injection for knee osteoarthritis.
Perineural Injection Therapy (PIT)
Perineural injection therapy involves injections placed just beneath the skin near areas of nerve-related discomfort. A non-pharmacological dextrose solution (D5W, 5% dextrose in sterile water) may be used. The technique is considered with the goal of supporting comfort and function in appropriate patients.
A consultation is needed to determine whether this option is appropriate for you.
Talk with Dr. Perrine about your options
Every case is different. Dr. Perrine will discuss an approach based on your condition, history, and goals during a consultation.
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This page provides general information and is not a substitute for individualized medical advice, diagnosis, or treatment. Treatment recommendations are made only after an appropriate clinical evaluation. Individual results vary.


